IOCB Prague

Tomáš Slanina Group

Redox Photochemistry
Research Group
Senior
CHEM cluster

About our group

The research of our laboratory focuses on the development of small organic molecules that undergo electron transfer and/or can be activated by light. This interdisciplinary research field combines organic synthesis, electrochemistry, spectroscopy, physical chemistry and mechanistic investigations of light-triggered processes. Our main goal is to precisely control redox reactions and electron transfer in space and time, reversibly transfer charge between defined redox centres and develop methods for stabilization of organic radicals and radical ions. We aim to use them in various applications ranging from redox sensors to functionalized surfaces, molecular electronic devices and smart materials.

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Publications

All publications
Self-Sensitized Fulgimides with Selective Multiplicity-Based Three-State Photoswitching
Self-Sensitized Fulgimides with Selective Multiplicity-Based Three-State Photoswitching
Chemistry - A European Journal 31 (27): e202500678 (2025)
Precise control over excited-state multiplicity is a powerful strategy for controlling photochemical reactivity, particularly in multimodal systems where different multiplicities lead to distinct reaction products. Here, we present a multiplicity-sensitive, multimodal, fulgimide-based system capable of three-state photoswitching both in solution and in solid state. With the aim of suppressing singlet-state sensitization, we rationally designed an intramolecularly sensitized system that enables triplet-exclusive energy transfer – a crucial feature for selective multiplicity-dependent reactivity. Our findings provide insights into the underlying principles of intramolecular triplet-exclusive sensitization and its application in controlling three-state photoswitching in unimolecular systems.
Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration
eLife 13: RP97255 (2024)
BODIPY phototether enables oligonucleotide cyclization and subsequent deprotection by tissue-transparent red light
Chemical Communications 60 (32): 4366–4369 (2024)
Restricting Intramolecular Motion Converts Non-Fluorescent Semicroconaine Dyes into Turn-On Aggregation-Induced Emission Probes
Materials Chemistry Frontiers 2025: Early View