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IOCB Prague

Tomáš Slanina Group

Redox Photochemistry
Research Group
Junior
CHEM cluster

About our group

The research of our laboratory focuses on the development of small organic molecules that undergo electron transfer and/or can be activated by light. This interdisciplinary research field combines organic synthesis, electrochemistry, spectroscopy, physical chemistry and mechanistic investigations of light-triggered processes. Our main goal is to be able to precisely control redox reactions and electron transfer in space and time, reversibly transfer charge between defined redox centres and develop methods for stabilization of organic radicals and radical ions. We aim to use them in various applications ranging from redox sensors to functionalized surfaces, molecular electronic devices and smart materials.
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Publications

All publications
In Search of the Perfect Photocage: Structure–Reactivity Relationships in meso-Methyl BODIPY Photoremovable Protecting Groups
In Search of the Perfect Photocage: Structure–Reactivity Relationships in meso-Methyl BODIPY Photoremovable Protecting Groups
T. Slanina
P. Shrestha
E. Palao
J. Kand
J. A. Peterson
A. S. Dutton
N. Rubinstein
R. Weinstain
A. H. Winter
P. Klán
Journal of the American Chemical Society 139 (42): 15168-15175 (2017)
A detailed investigation of the photophysical parameters and photochemical reactivity of meso-methyl BODIPY photoremovable protecting groups was accomplished through systematic variation of the leaving group (LG) and core substituents as well as substitutions at boron. Efficiencies of the LG release were evaluated using both steady-state and transient absorption spectroscopies as well as computational analyses to identify the optimal structural features. We find that the quantum yields for photorelease with this photocage are highly sensitive to substituent effects. In particular, we find that the quantum yields of photorelease are improved with derivatives with higher intersystem crossing quantum yields, which can be promoted by core heavy atoms. Moreover, release quantum yields are dramatically improved by boron alkylation, whereas alkylation in the meso-methyl position has no effect. Better LGs are released considerably more efficiently than poorer LGs. We find that these…
Rhodamine 6G Radical: A Spectro (Fluoro) Electrochemical and Transient Spectroscopic Study
T. Slanina
T. Oberschmid
ChemCatChem 10 (18): 4182-4190 (2018)
A ‘photorelease, catch and photorelease’ strategy for bioconjugation utilizing a p-hydroxyphenacyl group
D. Madea
T. Slanina
P. Klán
Chemical Communications 52 (87): 12901-12904 (2016)
Transition-Metal-Free CO-Releasing BODIPY Derivatives Activatable by Visible to NIR Light as Promising Bioactive Molecules
E. Palao
T. Slanina
L. Muchová
T. Šolomek
L. Vítek
P. Klán
Journal of the American Chemical Society 138 (1): 126-133 (2016)